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DELability β Protein Assessment for DEL Screening
Over the last 5 years, biopharma has fully embraced the use of DNA-encoded libraries (DELs) for hit identification for all...
Does Size Matter in DEL Screening?
One of the most attractive aspects of DNA-encoded library (DEL) technology is the vast number of compounds that can be...
Software and Science Go Hand in Hand at X‑Chem: Informatics Tools for a Scalable and Effective DEL Platform
From the very beginnings of X-Chem, we recognized the need to invest in software capabilities. DNA-encoded library (DEL) technology generates...
X‑Chem Announces Strategic Collaboration with Astellas Pharma Across Multiple Therapeutic Areas
WALTHAM, Mass. β March 20 2017 β X-Chem, Inc. (X-Chem), a privately held biotechnology company applying its innovative drug discovery capabilities to the generation of novel small molecule therapeutics, announced the signing of a broad drug discovery collaboration with Astellas Pharma Inc. (Astellas). The collaboration will enable the discovery of novel lead compounds for complex drug targets of interest to Astellas from X-Chemβs growing collection of DNA-encoded DEXβ’ libraries containing over 120 billion compounds. This new partnership is X-Chemβs most expansive first-time alliance with a pharmaceutical company, and is aimed at tackling hard-to-drug targets across multiple therapeutic areas at Astellas.
X‑Chem and Excelraβs GOSTAR Join Forces to Advance Drug Discovery for Challenging Targets
LONDON and HYDERABAD, India; Feb. 9, 2022 β A new collaboration between data science and analytics leader, Excelra, and artificial...
Proof of Concept: DEL for PROTACs
DNA-Encoded Chemical Library Screening Is a Great Tool for Identifying Novel Binders Suitable for Bispecific Degraders The Value of DEL...
Front-End Developer (London, United Kingdom)
The Opportunity: X-Chem London is seeking a candidate for the position of Front End Developer. This is a remote position....