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ZebiAI Therapeutics, Inc. and X‑Chem Enter into Strategic Agreement to Enable Validation of Novel Therapeutic Targets and Acceleration of Drug Candidate Discovery

January 13, 2020

New venture capital-backed artificial intelligence company to utilize X-Chem’s leading DNA encoded library screening service WALTHAM, Mass. – ZebiAI Therapeutics, Inc. and X-Chem, Inc., both of Waltham, MA, and privately held companies, today announced a multiyear service and license agreement. The agreement provides ZebiAI access to X-Chem’s proprietary DNA Encoded Library technology (DEXβ„’) for the discovery of novel small molecules to support ZebiAI’s Chemome Initiative – the identification of probe molecules for novel targets – and drug candidate identification to build upon discoveries from the Chemome effort. The collaboration additionally marks the establishment of ZebiAI Therapeutics alongside a funding round led by Anterra Capital.

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X‑Chem spin-off X-Biotix Therapeutics Completes $7 million Series A Financing

April 24, 2018

WALTHAM, Mass. April 24, 2018 – Small molecule drug discovery specialist X-Chem, Inc. (XChem) today announced that its spin-out company X-Biotix Therapeutics, Inc. (X-Biotix) has secured $7 million in a Series A financing from a group of private investors. X-Biotix, launched in 2017 out of X-Chem by Ramani Varanasi, Ph.D. and faculty members in the Department of Microbiology and Immunobiology at Harvard Medical School, plans to use the financing to advance its pipeline of novel antibiotics targeting Gram-negative bacteria. The company leverages the research of its scientific founders in essential biological pathways in bacteria and X-Chem’s DNA-encoded small molecule discovery platform.

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ALK-AbellΓ³ and X‑Chem Announce Drug Discovery Collaboration

February 6, 2020

WALTHAM, Mass. – February 5, 2019 - X-Chem, Inc. (X-Chem), a privately held biotechnology company focused on applying its next-generation, industry-leading DNA-Encoded library (DEXTM) drug discovery platform to the generation of novel small molecule therapeutics, announced today a drug discovery partnership with ALK-AbellΓ³ A/S (ALK), a Danish pharmaceutical company focused on the prevention and treatment of allergies. This collaboration will focus on the discovery of small molecule drug products to treat broad ranging allergies.