Bring advanced discovery tools in-house without the buildout
Access the same high-performance libraries and reagents used across X-Chem’s platform. These products are ready to support your next screen, synthesis, or internal DEL initiative.
ReadiDEL – Plug‑and‑Play DELs
Boost your screening with high-quality, ready-to-screen libraries
ReadiDELs are off-the-shelf DNA-encoded libraries built using XChem’s proprietary chemistries and optimized for atom economy and developability
What Sets ReadiDELs Apart
- Access 40+ curated libraries totaling over 15 billion compounds, with new content added regularly
- Libraries optimized for lead-like and drug-like properties to accelerate downstream optimization
- Delivered with full tag-to-chemistry keys and aliquots to support thousands of screening conditions
- Backed by decades of DEL innovation and 100+ licensed discovery programs worldwide
Ideal For:
- Teams expanding capability quickly
- Projects that need high-efficiency hit generation
- A trusted foundation for building and validating DEL screening workflows
Upgrade Your Library Design with Purpose-Built Building Blocks
ReadiBLOX is an ever-growing catalog of 640+ specially designed DEL-compatible building blocks created to elevate library diversity and hit quality.
A library of DEL Building Blocks
Built for Successful DEL Screening
- Bi- and tri-functional building blocks increase chemical complexity and novelty
- High Fsp3, low molecular weight, and drug-like features improve hit-to-lead progression
- Validated for DEL workflows to streamline synthesis and screening
Common Uses:
- Complement existing DELs with cutting-edge chemotypes
- Build or refresh in-house DELs with optimized building blocks
- Enhance diversity in targeted screens or modality-specific libraries
Box plot sampling of one ReadiDEL
How ReadiDELs and ReadiBLOX Support Your Discovery Workflow
| Discovery Challenge | ReadiDEL Solution | ReadiBLOX Solution |
|---|---|---|
| Limited access to high-quality libraries | Access ready-to-screen libraries with full tag-to-chemistry keys | Instantly expand existing DELs with novel, high-performing building blocks |
| Lack of chemical diversity in screens | Leverage curated, property-optimized DEL designs | Add depth and novelty through AI-informed block selection |
| Low-quality or noisy early hits | Start with consistent, validated libraries that reduce false positives | Elevate hit-to-lead potential with blocks designed for developability |
(Scroll left and right to view)
How Teams Like Yours Are Using ReadiDELs and ReadiBLOX
Building Internal DEL Capabilities
See how biopharma leaders like Roche, AstraZeneca, and Enko use X-Chem’s DELs to strengthen their pipelines and build internal screening platforms.
AI + DEL Capabilities
Our DELs and AI modeling approaches helped identify potent ERα and DCAF1 inhibitors in an oncology program—highlighting how these tools combine to produce actionable results.
Purpose-Built for Integrated Discovery
ReadiDELs and ReadiBLOX are designed to fit seamlessly into a modern, connected discovery process. One where data, design, and decisions are closely aligned.
- ReadiDELs deliver high-quality hits from expertly crafted, diverse libraries
- ReadiBLOX enhance your internal DEL efforts with AI-informed, chemically rich building blocks
- Both support workflows that combine DEL data with computational modeling, predictive analytics, and medicinal chemistry to streamline hit-to-lead progression
Whether you’re running your own screens or supplementing internal libraries, these tools help you move from data to decision faster. With greater clarity and more confidence at every step.
