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Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition

December 20, 2020

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Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry

July 25, 2020

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Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding

July 11, 2020

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Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry.

May 27, 2019

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Asymmetric Synthesis of a Potent CXCR7 Modulator Featuring a Hindered Tertiary β-Amino Amide Stereocenter

August 15, 2018

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Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the Target

January 9, 2018

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Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action

October 18, 2017

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Structural insight into allosteric modulation of protease-activated receptor 2

April 26, 2017

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Pharmacological property optimization for allosteric ligands: A medicinal chemistry perspective.

April 3, 2017

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Discovery of a potent BTK inhibitor with a novel binding mode using parallel selections with a DNA-encoded chemical library.

January 5, 2017